Medicine Description
Description : Alizapride is a dopamine antagonist with prokinetic and antiemetic effects Indication : used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Mechanism of action : The anti-emetic action of Alizapride is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone (CTZ) in the central nervous system (CNS)�this action prevents nausea and vomiting triggered by most stimuli. Structurally similar to metoclopramide and, therefore, shares similar other atributres related to emesis and prokinetics. Half life : 3 hours