About Linezolid Oxazolidinone derivative, reversible, nonselective monoamine oxidase inhibitor, Antibiotic. Mechanism of Action of Linezolid Linezolid binds to the 23 S fraction of 50 S ribosome and inhibit the formation of 70S initiation complex. Indications for Linezolid 1.Skin and soft tissue infection 2.Pneumonia 3.Wound infection 4.Bactremia 5.Respiratory tract infection 6.Septicaemia 7.Vancomycin resistant enterococcal infection Typical Dosage for Linezolid Adult: 800 - 1200 mg/day in two divided dose for 1 - 2 week