Medicine Description
About Isoxsuprine A beta-adrenergic agonist, Tocolytic agent,Peripheral vasodilator. Mechanism of Action of Isoxsuprine The drug exerts vasodilatory and smooth muscle relaxant action through acting as a beta adrenergic receptor agonist. It relaxes veins and arteries and causes dilatation and thus improves blood flow through them. It causes uterine relaxation due to it`s direct smooth muscle relaxant action. Indications for Isoxsuprine 1. Cerebral and peripheral vascular diseases 2. Prevention of premature labour and threatened abortion. Typical Dosage for Isoxsuprine Cerebral and peripheral vascular diseases: Oral: Starts with 20mg- 6th hourly. Reduces the dosage up to 10mg 8th hourly based on patient`s response. I.V.: Initially at an infusion rate of 0.3mg/minute. Then adjust the dosage based on the patient`s response. I.M.: Initially 5mg 8th hourly and gradually increases to 10 to 20mg 8th hourly.