About Calcium Glubionate Nutritional medicine, Mineral,Calcium salt Mechanism of Action of Calcium Glubionate Increases serum calcium level through direct effects on bone, kidney, and GI tract. Decreases osteoclastic osteolysis by reducing mineral release and collagen breakdown in bone. Pharmacokinets of Calcium Glubionate Absorption: Actively absorbed from gastrointestinal tract ionized form and vitamin D required for its absorption Distribution: Crosses the placenta, Appears in breast milk Excretion: Mainly in feces as unabsorbed calcium with 20% eliminated by the kidneys