About Ketoprofen NSAID, propionic acid derivative, Analgesic,antipyretic,antiinflammatory. Mechanism of Action of Ketoprofen It inhibits cyclo oxygenase enzymes both COX1 and COX2.These cyclooxygenase enzyme catalyses the synthesis of prostaglandins from arachidonic acid in the tissue. These inhibition produces its analgesic, antipyretic and anti inflammatory effects. It can also stabilize the lysosomal membrane. It is a Non Steroidal Anti Inflammatory Drug. It is a propionic acid derivative. Indications for Ketoprofen 1. Rheumatoid arthritis 2. Osteo arthritis 3. Pain due to dysmenorrhea 4. Treatment for exacerbations of musculo skeletal, periarticular and soft tissue disorders 5. Migraine 6. Gout-Acute attack